Rick Moranis
Matt Frewer
Marcia Strassman
Kristine Sutherland
Thomas Wilson Brown
Jared Rushton
Amy O'Neill
Robert Oliveri
Carl Steven
Mark L. Taylor
Rick Moranis as Wayne Szalinski
Matt Frewer as Russell 'Russ' Thompson, Sr. (Big Russ Thompson)
Marcia Strassman as Diane Szalinski
Kristine Sutherland as Mae Thompson
Thomas Wilson Brown as Russell 'Russ' Thompson, Jr. (Little Russell Thompson) (as Thomas Brown)
Jared Rushton as Ronald 'Ron' Thompson
Amy O'Neill as Amy Szalinski
Robert Oliveri as Nick Szalinski
Carl Steven as Tommy Pervis
Mark L. Taylor as Donald 'Don' Forrester
Kimmy Robertson as Gloria Forrester
Lou Cutell as Dr. Brainard
Laura Waterbury as Female Cop
Trevor Galtress as Male Cop
Martin Aylett as Harold Boorstein