Keke Palmer
Laurence Fishburne
Angela Bassett
Curtis Armstrong
J.R. Villarreal
Sean Michael
Sahara Garey
Lee Thompson Young
Jumper Lark
Julito McCullum
Keke Palmer as Akeelah
Laurence Fishburne as Dr. Larabee
Angela Bassett as Tanya Anderson
Curtis Armstrong as Mr. Welch
J.R. Villarreal as Javier
Sean Michael as Dylan
Sahara Garey as Georgia
Lee Thompson Young as Devon
Jumper Lark as Young Reporter
Julito McCullum as Terrence
Erica Hubbard as Kiana
Eddie Steeples as Derrick-T
Dalia Phillips as Ms. Cross
Tzi Ma as Mr. Chiu
Jeris Poindexter as Steve