Steven Jay Blum
Martin Halm
Bruno Mullenaerts
Kôichi Yamadera
Beau Billingslea
Unshô Ishizuka
Megumi Hayashibara
Wendee Lee
Yolanda Quesada
Marion Sawatzki

Steven Jay Blum as Spike Spiegel (English version) (voice: English version) (as Steven Blum)
Martin Halm as Spike Spiegel (voice: German version)
Bruno Mullenaerts as Spike Spiegel (voice: French version)
Kôichi Yamadera as Spike Spiegel (voice: Japanese version)
Beau Billingslea as Jet Black (voice: English version)
Unshô Ishizuka as Jet Black (voice: Japanese version)
Megumi Hayashibara as Faye Valentine (voice: Japanese version)
Wendee Lee as Faye Valentine (voice: English version)
Yolanda Quesada as Faye Valentine (voice: Spanish version)
Marion Sawatzki as Faye Valentine (voice: German version)
Sabine Bohlmann as Edward (Ed) (voice: German version)
Melissa Charles as Edward (Ed) (voice: English version) (as Melissa Fahn)
Stéphane Flamand as Edward (Ed) (voice: French version)
Aoi Tada as Edward (Ed) (voice: Japanese version)
Jennifer Hale as Electra (voice: English version)