Hank Azaria
Ben Stiller
William H. Macy
Geoffrey Rush
Janeane Garofalo
Greg Kinnear
Tom Waits
Paul Reubens
Claire Forlani
Eddie Izzard
Hank Azaria as The Blue Raja
Ben Stiller as Mr. Furious
William H. Macy as The Shoveller
Geoffrey Rush as Casanova Frankenstein
Janeane Garofalo as The Bowler
Greg Kinnear as Captain Amazing/Lance Hunt
Tom Waits as Dr. A. Heller
Paul Reubens as The Spleen
Claire Forlani as Monica the Waitress
Eddie Izzard as Tony P.
Kel Mitchell as The Invisible Boy
Wes Studi as The Sphinx
Lena Olin as Dr. Annabel Leek
Ricky Jay as Victor Weems
Louise Lasser as Violet, The Blue Raja's Mom