Ray Romano
John Leguizamo
Denis Leary
Goran Visnjic
Jack Black
Cedric the Entertainer
Stephen Root
Diedrich Bader
Alan Tudyk
Lorri Bagley
Ray Romano as Manfred (voice)
John Leguizamo as Sid (voice)
Denis Leary as Diego (voice)
Goran Visnjic as Soto (voice)
Jack Black as Zeke (voice)
Cedric the Entertainer as Carl (voice)
Stephen Root as Rhino / Start (voice)
Diedrich Bader as Saber-Toothed Tiger (voice)
Alan Tudyk as Oscar / Dab the Dodo (voice)
Lorri Bagley as Female Sloth (voice)
Jane Krakowski as Female Sloth (voice)
Peter Ackerman as Dodo / Macrauchenia (voice)
P.J. Benjamin as Dodo (voice)
Josh Hamilton as Dodo / Aardvark (voice)
Chris Wedge as Dodo / Scrat (voice)