Demián Bichir
Rodrigo Santoro
Benicio Del Toro
Catalina Sandino Moreno
María D. Sosa
Raúl Beltrán
Raúl 'Pitín' Gómez
Paty M. Bellott
Othello Rensoli
Franka Potente
Demián Bichir as Fidel Castro
Rodrigo Santoro as Raúl Castro
Benicio Del Toro as Ernesto Che Guevara
Catalina Sandino Moreno as Aleida March
María D. Sosa as Aleidita
Raúl Beltrán as Bolivian Customs Agent #1
Raúl 'Pitín' Gómez as Bolivian Customs Agent #2
Paty M. Bellott as Woman at Airport
Othello Rensoli as Pombo (Harry Villegas Tamayo)
Franka Potente as Tania (Haydee Tamara Bunke Bider)
Norman Santiago as Tuma (Carlos Coello)
Joaquim de Almeida as President René Barrientos
Pablo Durán as Pacho (Alberto Fernández Montes de Oca)
Ezequiel Diaz as Loro (Jorge Vázquez Viaña) (as Ezequiel Díaz)
Juan Salinas as Polo (Apolinar Aquino Quispe)